Browsing by Author "Chaves, Beatriz"
Now showing items 1-12 of 12
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Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8⁺ T cells
Kamnev, Anton et al. | Date Issued: 2024 -
Development and characterization of Anti-VLA4 Monoclonal Antibody as a potential biopharmaceutical for the treatment of Multiple Sclerosis
Castro, Vitória Fernandes de et al. | Date Issued: 2023 -
Development of New Potential Inhibitors of 1 Integrins through In Silico Methods—Screening and Computational Validation
Vasconcelos, Disraeli et al. | Date Issued: 2022 -
Generation of a scFv antagonistic to VLA-4 integrin as potential therapeutic target in muscular dystrophies: in silico phase
Chaves, Beatriz et al. | Date Issued: 2017As integrinas α4β1 ou VLA-4 são encontradas em membranas de monócitos e linfócitos T. A sua participação na migração de leucócitos é crucial para doenças inflamatórias. Além disso, essas proteínas também são encontradas ... -
Guidelines To Predict Binding Poses of Antibody−Integrin Complexes
Chaves, Beatriz et al. | Date Issued: 2020 -
In silico development of a scFv antagonistic to α4β1 integrin
Silva, João Hermínio Martins da et al. | Date Issued: 2016 -
In silico directed evolution in antibody engineering: a promising approach to improvement antitumor biopharmaceuticals
Chaves, Thiago Santos et al. | Date Issued: 2019 -
Integrin-directed antibody-based immunotherapy: focus on VLA-4
Savino, Wilson et al. | Date Issued: 2021 -
Production of a scFv antagonistic to VLA-4 protein as a potential biopharmaceutical for chronic inflammatory diseases
Chaves, Beatriz et al. | Date Issued: 2018 -
Produção e avaliação de um scFv bloqueador da integrina VLA-4 como potencial biofármaco para o tratamento de doenças inflamatórias crônicas
Chaves, Beatriz | Date Issued: 2019A integrina Α4β1, ou VLA-4, é uma proteína heterodimérica transmembranar presente, principalmente, na superfície de linfócitos T e monócitos. Por mediar a transmigração dessas células a partir do endotélio para o sítio ... -
Systemic inflammation and normocytic anemia in DOCK11 deficiency
Block, Jana et al. | Date Issued: 2022 -
VLA-4 as a Central Target for Modulating Neuroinflammatory Disorders
Jurberg, Arnon Dias et al. | Date Issued: 2021